In vitro effects of estrogen and progesterone containing drugs on human erythrocyte carbonic anhydrase I and II isozymes in women smokers and nonsmokers


Taskin M. I. , Bilen C. , Ergun A., Gencer N., Inceboz U.

JOURNAL OF THE CHINESE MEDICAL ASSOCIATION, cilt.78, ss.513-519, 2015 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 78 Konu: 9
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.jcma.2015.03.014
  • Dergi Adı: JOURNAL OF THE CHINESE MEDICAL ASSOCIATION
  • Sayfa Sayısı: ss.513-519

Özet

Background: Carbonic anhydrases (CAs), a group of metalloenzymes, are involved in numerous physiological and pathological processes such as acid base balance, gluconeogenesis, lipogenesis, ureagenesis, electrolyte secretion in various tissues, bone resorption and calcification, and tumorigenicity. In the current study, we aimed to determine and compare possible alterations in the activity of carbonic anhydrase I (CA I) and carbonic anhydrase II (CA II) isozymes by using estrogens and progestagens in female smokers and nonsmokers.