The synthesis and photophysicochemical behaviour of novel water-soluble cationic indium(III) phthalocyanine

Durmus M., Erdogmus A., Ogunsipe A., Nyokong T.

DYES AND PIGMENTS, vol.82, no.2, pp.244-250, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 82 Issue: 2
  • Publication Date: 2009
  • Doi Number: 10.1016/j.dyepig.2009.01.008
  • Journal Name: DYES AND PIGMENTS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.244-250
  • Keywords: Indium(III) phthalocyanine, Synthesis, Photophysics, Photochemistry, Photodynamic therapy, Singlet oxygen, SINGLET OXYGEN, QUANTUM YIELDS, SUBCELLULAR-LOCALIZATION, PHOTOCHEMICAL PROPERTIES, ZINC PHTHALOCYANINE, FLUORESCENCE, METAL, STATE, COMPLEXES, PORPHYRIN
  • Yıldız Technical University Affiliated: Yes

Abstract

The syntheses and characterization of 2,3-octakis-(3-pyridyloxyphthalocyaninato) indium(III) and quaternized 2,3-octakis-(3-pyridyloxyphthalocyaninato) indium(III) are described. The ground state electronic absorption spectra, photophysics and photochemistry of both dyes in DMSO as well as that of the quaternized compound in aqueous solution are also presented. A comparison of the photophysical and photochemical parameters of the two dyes revealed that quaternized 2,3-octakis-(3-pyridyloxyphthalocyaninato) indium(III) was a better photosensitizer than its unquaternized counterpart. The quantum yield values of fluorescence (Phi(F)), triplet state formation (Phi(T)) and singlet oxygen formation (Phi(Delta)) for the cationic dye were found to be 0.03, 0.68 and 0.66 respectively in DMSO; these values were higher than those for 2,3-octakis-(3-pyridyloxyphthalocyaninato) indium(III), which exhibited values of 0.02, 0.66 and 0.63, respectively in DMSO. The values for the cationic dye in aq. solution were 0.02, 0.59 and 0.56 respectively, suggesting that the water-soluble quaternized 2,3-octakis-(3-pyridyloxyphthalocyaninato) indium(III) offers potential as a photosensitizer in photodynamic therapy treatment. (C) 2009 Elsevier Ltd. All rights reserved.