Numerical Assessment of the Effects of Ductus Arteriosus Closure on Cerebral Blood Flow Rate in Newborn Infants

Bozkurt S., Ayten U. E.

2023 Medical Technologies Congress (TIPTEKNO), Gazimagusa, Kıbrıs (Kktc), 10 - 12 Kasım 2023, ss.1-4

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Doi Numarası: 10.1109/tiptekno59875.2023.10359198
  • Basıldığı Şehir: Gazimagusa
  • Basıldığı Ülke: Kıbrıs (Kktc)
  • Sayfa Sayıları: ss.1-4
  • Yıldız Teknik Üniversitesi Adresli: Evet

Özet

The physiological changes within a few days after birth is vital importance for health of newborn infants. Ductus arteriosus, which is a vessel connection between aorta and pulmonary arteries, closes in the first day life of term infants. In this study, a lumped-parameter model was used to evaluate change of cerebral blood flow rate due to closure of ductus arteriosus within a 24 hour after birth in term infants. The model includes heart chambers, systemic circulatory system, pulmonary circulatory system and a complete circle of Willis. The cerebral blood flow rate was 122 mL/min in the cardiovascular system model simulating period right after birth and it increased to 151 mL/min in the cardiovascular system model simulating 24th hour after birth. Also, the blood flow rate through internal carotid arteries increased from 47 mL/min to 58 mL/min and the blood flow rate through vertebral arteries increased from 14 mL/min to 17 mL/min. The results showed that the closure of the ductus arteriosus causes cerebral blood flow rate to increase in term infants.