Research Information System
Bulgarian Chemical Communications, vol.57, no.3, pp.245-248, 2025 (Scopus)
The human body consists of systems, systems are organs, organs are cells and extracellular matrix. The extracellular matrix has an important role in the human body with the task of connecting cells to each other. Due to various reasons, diseases in which the extracellular matrix is damaged have been witnessed from the past to the present. Tissue engineers are in research to improve and prevent this damage. As a result of these researches, the production of tissue scaffolds has started. Tissue scaffolds are structures designed to mimic the extracellular matrix. These scaffolds can perform functions belonging to the extracellular matrix, such as providing mechanical strength, helping to establish communication with the surrounding tissue to respond to physiological and biological changes, as well as forming suitable adhesion surfaces for cells. They may also contribute to the regeneration of the true extracellular matrix. Tissue scaffolds can be produced by many methods and one of them is the gas foaming technique. In our study, tissue scaffolds produced by this method were used and it was aimed to increase the porosity of these scaffolds. In the experiments, tissue scaffolds were obtained by electro-spinning method and NaBH4-methanol solution was used for gas foaming method. As a result, it was observed that the porosity properties of the tissue scaffolds inflated in 0.1M solution were increased. These observations were determined and documented by the analysis results.