Investigation of alumina doped 45S5 glass as a bioactive filler for experimental dental composites

Elalmış Y., Karakuzu Ikizler B., Kılıç Depren S., Yücel S., Aydın İ.

INTERNATIONAL JOURNAL OF APPLIED GLASS SCIENCE, vol.12, no.3, pp.313-327, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.1111/ijag.16043
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Applied Science & Technology Source, Compendex, INSPEC
  • Page Numbers: pp.313-327
  • Keywords: alumina, alumina doped bioactive glass, bioactive glass, dental composite, MELT-DERIVED 45S5, MECHANICAL-PROPERTIES, SILICA, AL2O3
  • Yıldız Technical University Affiliated: Yes


This study aimed to investigate the effects of inclusion of Al2O3-doped bioactive glass (BG) and silane treatment on physical properties and bioactivity behavior of resin-based experimental dental composites (EDCs). Melt-derived 45S5 BG and alumina doped 45S5 BG were prepared and incorporated into EDCs with and without silanization. EDCs prepared were subjected to three-point bending, microhardness, water sorption (WS), solubility (S), and bioactivity tests. Using non-silanized Al2O3-doped BG in EDCs resulted in improved flexural strength (FS), flexural modulus (FM), and microhardness and decreased bioactivity compared to EDCs containing non-silanized BG. There was no significant difference (p < 0.05) between WS and S results of non-silanized glass containing EDCs. Using silanized BG and Al2O3-doped BG resulted in improved FS and FM, decreased WS, S, and bioactivity. Addition of Al2O3-doped BG as a possible bioactive filler to EDCs improved mechanical performance while slightly decreasing bioactivity compared to BG containing EDCs.