Drug-drug interaction discovery and demystification using Semantic Web technologies

Noor, Adeeb; Assiri, Abdullah; Ayvaz, Serkan; Clark, Connor; Dumontier, Michel

doi:10.1093/jamia/ocw128

Drug-drug interaction discovery and demystification using Semantic Web technologies

Noor A., Assiri A., Ayvaz S., Clark C., Dumontier M.

JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION, vol.24, no.3, pp.556-564, 2017 (SCI-Expanded, SSCI, Scopus)

Publication Type: Article / Article
Volume: 24 Issue: 3
Publication Date: 2017
Doi Number: 10.1093/jamia/ocw128
Journal Name: JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
Page Numbers: pp.556-564
Keywords: drug interactions, pharmacovigilance, pharmacologic actions, Semantic Web, ELECTRONIC HEALTH RECORDS, COLORECTAL-CANCER, P-GLYCOPROTEIN, CYTOCHROME-P450, TERMINOLOGY, METABOLISM, ASPIRIN, EVENTS, PHARMACOMETRICS, KNOWLEDGEBASE
Yıldız Technical University Affiliated: No

Abstract

Objective: To develop a novel pharmacovigilance inferential framework to infer mechanistic explanations for asserted drug-drug interactions (DDIs) and deduce potential DDIs.