Drug-drug interaction discovery and demystification using Semantic Web technologies

Noor A., Assiri A., Ayvaz S., Clark C., Dumontier M.

JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION, cilt.24, sa.3, ss.556-564, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1093/jamia/ocw128
  • Dergi Adı: JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.556-564
  • Anahtar Kelimeler: drug interactions, pharmacovigilance, pharmacologic actions, Semantic Web, ELECTRONIC HEALTH RECORDS, COLORECTAL-CANCER, P-GLYCOPROTEIN, CYTOCHROME-P450, TERMINOLOGY, METABOLISM, ASPIRIN, EVENTS, PHARMACOMETRICS, KNOWLEDGEBASE
  • Yıldız Teknik Üniversitesi Adresli: Hayır

Özet

Objective: To develop a novel pharmacovigilance inferential framework to infer mechanistic explanations for asserted drug-drug interactions (DDIs) and deduce potential DDIs.