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APPLIED MATHEMATICS AND COMPUTATION, vol.94, no.1, pp.73-81, 1998 (SCI-Expanded)
It is possible to write the equations governing a one-stage enzyme-catalysed reaction (according to Michaelis-Menten kinetics) quite easily, and deduce information about the steady-state flux in such a system. The situation is somewhat more complicated if several such reactions form a linear chain. We have applied Grobner-basis techniques to solve such systems and hence demonstrate the use of computer algebra as a powerful technique in enzyme kinetic analysis. (C) 1998 Elsevier Science Inc. All rights reserved.