Application of computer algebra techniques to enzyme kinetics


Bayram M.

APPLIED MATHEMATICS AND COMPUTATION, vol.94, no.1, pp.73-81, 1998 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 94 Issue: 1
  • Publication Date: 1998
  • Doi Number: 10.1016/s0096-3003(97)10028-5
  • Title of Journal : APPLIED MATHEMATICS AND COMPUTATION
  • Page Numbers: pp.73-81

Abstract

It is possible to write the equations governing a one-stage enzyme-catalysed reaction (according to Michaelis-Menten kinetics) quite easily, and deduce information about the steady-state flux in such a system. The situation is somewhat more complicated if several such reactions form a linear chain. We have applied Grobner-basis techniques to solve such systems and hence demonstrate the use of computer algebra as a powerful technique in enzyme kinetic analysis. (C) 1998 Elsevier Science Inc. All rights reserved.