Freeze-drying of pharmaceutical products: Research and development needs

Sadikoglu H., OZDEMIR M., SEKER M.

DRYING TECHNOLOGY, vol.24, no.7, pp.849-861, 2006 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 7
  • Publication Date: 2006
  • Doi Number: 10.1080/07373930600734018
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.849-861
  • Yıldız Technical University Affiliated: No


Significance of pharmaceutical formulation (choosing of correct excipients in optimal quantities), effects of glass transition temperature, importance of theoretical modeling of the process, benefits of optimal control, and the advantages of remote monitoring of the process are presented. Experimental and theoretical research and development needs for the freeze-drying of pharmaceutical products are proposed and discussed.