Freeze-drying of pharmaceutical products: Research and development needs

Sadikoglu H. , OZDEMIR M., SEKER M.

DRYING TECHNOLOGY, cilt.24, sa.7, ss.849-861, 2006 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Konu: 7
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1080/07373930600734018
  • Sayfa Sayıları: ss.849-861


Significance of pharmaceutical formulation (choosing of correct excipients in optimal quantities), effects of glass transition temperature, importance of theoretical modeling of the process, benefits of optimal control, and the advantages of remote monitoring of the process are presented. Experimental and theoretical research and development needs for the freeze-drying of pharmaceutical products are proposed and discussed.