SYNTHESIS OF NEW TANDOSPIRONE ANALOGUES CARRYING 1-(3-(TRIFLUOROMETHYL)PHENYL)PIPERAZINE

GÜNKARA, Ömer; Sucu, Bilgesu; Guleli, Muge; Ocal, Zehra

doi:10.1080/00397911.2013.865236

SYNTHESIS OF NEW TANDOSPIRONE ANALOGUES CARRYING 1-(3-(TRIFLUOROMETHYL)PHENYL)PIPERAZINE

Atıf İçin Kopyala

GÜNKARA Ö. T., Sucu B. O., Guleli M., Ocal N.

SYNTHETIC COMMUNICATIONS, cilt.44, sa.11, ss.1619-1628, 2014 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 44 Sayı: 11
Basım Tarihi: 2014
Doi Numarası: 10.1080/00397911.2013.865236
Dergi Adı: SYNTHETIC COMMUNICATIONS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1619-1628
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Yıldız Teknik Üniversitesi Adresli: Evet

Özet

New tandospirone analogues containing a 1-[3-(trifluoromethyl) phenyl] piperazine (TFMPP) moiety have been synthesized by hydroarylation reactions with Pd(OAc)(2). The perhydroisoindole derivatives were obtained by the reaction of reduced starting material with aryl-(heteroaryl) iodides under the same conditions. Spiro-1,3-indandionolylpyrrolidine derivatives having an array of stereocenters are reported.