Optimization of Different Surface Modifications for Binding of Tumor Cells ina Microfluidic Systems 10.30621/jbachs.2019.601

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Meco H. E., Karadag A., Omeroglu S., Kocal G. C., Oruc M. E., Üvet H., ...More

JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES, vol.3, pp.73-77, 2019 (Peer-Reviewed Journal)

  • Publication Type: Article / Article
  • Volume: 3
  • Publication Date: 2019
  • Journal Name: JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES
  • Journal Indexes: TR DİZİN (ULAKBİM)
  • Page Numbers: pp.73-77
  • Yıldız Technical University Affiliated: Yes

Abstract

 

 Microfluidic technology is a fast-growing area and provide high-efficient MEMS (Micro-Electro-Mechanical-Systems) sensor integration platform that helps to advance healthcare systems. Due to proper the chemical and mechanical properties of polymers, PDMS (Polydimethylsiloxane) (6) and PMMA (Poly-methyl-methacrylate), they became on the best candidate for health care studies in microfluidic studies (7). Besides, they perform great optical properties for observation of living cell experiments. To increase their performance, surface interactions works with cells, modification techniques are widely used in microfluidic chips. In this paper, our primary purpose is to modify such polymers and glass with matrigel, PDA and APTES so as to increase cell-surface interaction.