Preparation of 1,2- and 1,4-dihydro derivatives of 6,7-dimethyl-2,3-diphenylquinoxaline via its dianion formed by reductive metallation


Kaban S. , AYDOĞAN F.

MONATSHEFTE FUR CHEMIE, cilt.139, ss.669-672, 2008 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 139 Konu: 6
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1007/s00706-007-0812-1
  • Dergi Adı: MONATSHEFTE FUR CHEMIE
  • Sayfa Sayıları: ss.669-672

Özet

Treatment of 6,7-dimethyl-2,3-diphenylquinoxaline with sodium in tetrahydrofuran formed a monomeric dianion. The chemical behavior of this dianion was investigated by a variety of reagents. As the result, alkylation reactions gave 1,2-dihydro derivatives, while acylation reactions occured at 1,4-positions. Annulation of the pyrazine ring system was accomplished by treating the dianion with oligomethylene dichlorides, Cl(CH(2))(n)Cl, n = 2-4.