Synthesis and Potentiometric Sensor Applications of a Hydrazone Derivative Molecule: Fast and Selective Determination of Cobalt(II) Ions

Ozbek O., Kalay E., Cetin A., IŞILDAK Ö., TOKALI F. S., ASLAN O. N., ...More

CHEMISTRYSELECT, vol.7, no.28, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 28
  • Publication Date: 2022
  • Doi Number: 10.1002/slct.202201307
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier
  • Keywords: Cobalt(II), Hydrazone derivatives, Potentiometry, Sensors, Synthesis, ELECTRODE, EXTRACTION, COMPLEXES, CHLORINE, WATER
  • Yıldız Technical University Affiliated: Yes


In this study, a simple and highly selective potentiometric sensor has been developed for the determination of cobalt(II) ions based on a poly(vinly chloride) (PVC) membrane. As an ionophore, a hydrazone derivative molecule (3) was synthesized for the first time, and its characterization was completed using NMR, FT-IR and Q-TOF spectroscopic techniques. The developed sensor works well in the linear concentration range of 1.0x10(-6)-1.0x10(-1) M with Nernstian slope of 28.6 +/- 1.7 mV/decade of activity. The developed cobalt(II)-selective sensor has a low detection limit of 3.09x10(-7) M, and a very fast response time of 5 seconds. The sensor, which exhibits a highly selective behaviour towards cobalt(II) ions compared to other metal cations, works in the pH range of 6.0-10.0 without being affected by changes in pH. The developed sensor could be used as an indicator electrode in potentiometric titration of Co(II) ions with EDTA. Finally, the developed cobalt(II)-selective sensor was successfully used for the determination of Co(II) in various water samples.