Handbook of Polymers in Medicine, Masoud Mozafari Narendra Pal Singh Chauhan, Editör, Woodhead Publishing Limited , Chennai, ss.243-262, 2023
Polyurethane (PU) is one of the most popular polymeric materials and has gained great attention in biomedical fields owing to its extensive structure/property diversity. Among all the synthetic polymers, PUs show good biocompatibility as well as excellent mechanical, physical, and chemical properties. PU can be produced in various forms, such as composite, coating, foam, and elastomer by chemical reaction of the naturally or synthetically obtained diol (polyol), diisocyanate, and chain extender. The reaction between diisocyanates and polyols (polyesters or polyethers) is a key process for making various PU products. It is used in many biomedical fields ranging from cardiovascular implants such as blood filters and artificial hearts to biomedical test materials such as rigid PU foam blocks. Biocompatibility of PUs can be improved by the introduction of bio-molecules such as polysaccharides, proteins, and lipids. In this chapter, the production methods of PU polymers and biomedical applications will be discussed.
Polyurethane (PU) is one of the most popular polymeric materials and has gained great attention in biomedical fields owing to its extensive structure/property diversity. Among all the synthetic polymers, PUs show good biocompatibility as well as excellent mechanical, physical, and chemical properties. PU can be produced in various forms, such as composite, coating, foam, and elastomer by chemical reaction of the naturally or synthetically obtained diol (polyol), diisocyanate, and chain extender. The reaction between diisocyanates and polyols (polyesters or polyethers) is a key process for making various PU products. It is used in many biomedical fields ranging from cardiovascular implants such as blood filters and artificial hearts to biomedical test materials such as rigid PU foam blocks. Biocompatibility of PUs can be improved by the introduction of bio-molecules such as polysaccharides, proteins, and lipids. In this chapter, the production methods of PU polymers and biomedical applications will be discussed.