A facile synthesis of (+/-)-mintlactone
SYNTHETIC COMMUNICATIONS, vol.27, no.19, pp.3471-3476, 1997 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 27 Issue: 19
- Publication Date: 1997
- Doi Number: 10.1080/00397919708005649
- Journal Name: SYNTHETIC COMMUNICATIONS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.3471-3476
- Yıldız Technical University Affiliated: No
Abstract
(+/-)-Mintlactone has been synthesized by applying a novel effective synthetic sequence. 4-Methylcyclohexanone was subjected to acetoxylation with Pb(OAc)(4). Hydrolysis followed by reaction with 2-chloroprogionyl chloride,then treatment with triethyl phosphite and, finally, Horner-Emmons-type intramolecular cyclization afforded (+/-)-Mintlactone.