A facile synthesis of (+/-)-mintlactone

Tanyeli, Cihangir; Caliskan, Zerrin; Demir, Ayhan

doi:10.1080/00397919708005649

A facile synthesis of (+/-)-mintlactone

Tanyeli C., Caliskan Z., Demir A. S.

SYNTHETIC COMMUNICATIONS, cilt.27, sa.19, ss.3471-3476, 1997 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 27 Sayı: 19
Basım Tarihi: 1997
Doi Numarası: 10.1080/00397919708005649
Dergi Adı: SYNTHETIC COMMUNICATIONS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.3471-3476
Yıldız Teknik Üniversitesi Adresli: Hayır

Özet

(+/-)-Mintlactone has been synthesized by applying a novel effective synthetic sequence. 4-Methylcyclohexanone was subjected to acetoxylation with Pb(OAc)(4). Hydrolysis followed by reaction with 2-chloroprogionyl chloride,then treatment with triethyl phosphite and, finally, Horner-Emmons-type intramolecular cyclization afforded (+/-)-Mintlactone.