A facile synthesis of (+/-)-mintlactone

Tanyeli C., Caliskan Z., Demir A. S.

SYNTHETIC COMMUNICATIONS, vol.27, no.19, pp.3471-3476, 1997 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 19
  • Publication Date: 1997
  • Doi Number: 10.1080/00397919708005649
  • Journal Name: SYNTHETIC COMMUNICATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.3471-3476
  • Yıldız Technical University Affiliated: No

Abstract

(+/-)-Mintlactone has been synthesized by applying a novel effective synthetic sequence. 4-Methylcyclohexanone was subjected to acetoxylation with Pb(OAc)(4). Hydrolysis followed by reaction with 2-chloroprogionyl chloride,then treatment with triethyl phosphite and, finally, Horner-Emmons-type intramolecular cyclization afforded (+/-)-Mintlactone.