Polymer grafting onto magnetite nanoparticles by "click" reaction

Amici J., Kahveci M. Ü., Allia P., Tiberto P., Yağcı Y., Sangermano M.

JOURNAL OF MATERIALS SCIENCE, vol.47, no.1, pp.412-419, 2012 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1007/s10853-011-5814-z
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.412-419
  • Yıldız Technical University Affiliated: Yes


In this article, we described click chemistry methodology for the incorporation of biocompatible polymer chains to Magnetite nanoparticles (NPs). We used a reduction co-precipitation method to obtain Fe3O4 particles in aqueous solution. As a next step, magnetic NPs surface were modified by a silanization reaction with (3-bromopropyl)trimethoxysilane in order to introduce bromine groups on the particles surface which were converted to azide groups by the reaction with sodium azide. Acetylene functionalized poly(ethylene glycol) (a-PEG) and poly(epsilon-caprolactone) (a-PCL) were synthesized and grafted onto the surface of azide functionalized NPs via "click" reaction to obtain magnetic NPs. Success of the different functionalization processes at different stages was studied using Fourier Transform infrared spectroscopy (FTIR). The morphologies of magnetic NPs were further investigated by transmission electron microscopy (TEM). The magnetization and superparamagnetic behavior of naked Fe3O4 NPs and coated NPs at room temperature was investigated by the measurement of hysteresis curves using a Vibrating Sample Magnetometer (VSM).