A new coumarin based Schiff base fluorescence probe for zinc ion


ARVAS B. , Ucar B., Acar T., ARVAS M. B. , ŞAHİN Y. , AYDOĞAN F. , ...More

Tetrahedron, 2021 (Journal Indexed in SCI Expanded) identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2021
  • Doi Number: 10.1016/j.tet.2021.132127
  • Title of Journal : Tetrahedron

Abstract

© 2021Herein, a novel coumarin-based fluorescent probe (FS3) was designed, synthesized, and characterized. It exhibited significant fluorescence quenching in the presence of Zn2+ ions. Just a minor alteration occurred in the fluorescence intensity of FS3 in the presence of other metals studied. The limit of detection for the determination of Zn2+ by FS3 was calculated to be 3.43 × 10−9 M. Since the Job's graph of 1/(F0–F) and 1/[Zn2+] had a linear fit, it was determined that the binding stoichiometry between the FS3 and Zn2+ was 1:1. The association constant of the system was found to be 2.39 × 104 M−1 and confirmed by ESI-MS and FT-IR. It was demonstrated that the developed highly reversible sensor system works by performing real sample analysis. Moreover, the FS3 which has shown no toxicity and displayed a strong fluorescence image will act as an efficient and non-destructive sensor for the determination of Zn2+ in living organisms.