Microwave assisted synthesis of Jeffamine cored PAMAM dendrimers

Erturk A. S., TÜLÜ M., BOZDOĞAN A. E., Parali T.

EUROPEAN POLYMER JOURNAL, cilt.52, ss.218-226, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 52
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.eurpolymj.2013.12.018
  • Dergi Adı: EUROPEAN POLYMER JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.218-226
  • Anahtar Kelimeler: Amidation, Dendrimers, Liquid phase polymer retention (LPR), Microwave chemistry (MW), POLY(AMIDOAMINE) DENDRIMERS, ORGANIC-SYNTHESIS, POLYMER, CHEMISTRY, CARRIERS, SIZE
  • Yıldız Teknik Üniversitesi Adresli: Evet

Özet

This study reports the use of a new microwave assisted amidation method for the synthesis of Jeffamine cored poly (amidoamine) (PAMAM) dendrimers up to fourth generations. Reaction proceeding is monitored by attenuated total reflectance (ATR) without final purification. It was found that current method decreases the aminolysis time, and minimizes the excessive use of reagents and solvents. Synthesized dendrimers were purified by liquid-phase polymer-based retention (LPR) technique and characterized by H-1-NMR, C-13-NMR, EA, GPC and UV-VIS spectroscopy. (C) 2014 Elsevier Ltd. All rights reserved.