Physicochemical properties, molecular docking and global reactivity descriptors of manganese carbonyl complexes with imidazole ligands


Creative Commons License

Güngör G., Şakar D., Üstün E., Şahin N.

JOURNAL OF THE INDIAN CHEMICAL SOCIETY, vol.96, pp.1163-1168, 2019 (SCI-Expanded)

  • Publication Type: Article / Article
  • Volume: 96
  • Publication Date: 2019
  • Journal Name: JOURNAL OF THE INDIAN CHEMICAL SOCIETY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1163-1168
  • Yıldız Technical University Affiliated: Yes

Abstract

In this study, it was investigated that the solution behavior of two carbon monoxide releasing molecules; Mn(CO)3(bpy)(Nimidazole)]

PF6 (1), [Mn(CO)3(bpy)(N-methylimidazole)]PF6 (2) which showed anticancer activity via zetasizer properties such

as measuring particle size, electrophoretic mobility and zeta potential as a function of pH and determined the global reactivity

descriptors and molecular docking poses via computational chemistry. The activities of molecules in the different pHs were

checked by UV/Vis spectrophotometer.