Particle size and zeta potential investigation of synthetic peptide-protein conjugates


DERMAN S. , AKDESTE Z. M.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.40, ss.282-289, 2015 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 40 Konu: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1515/tjb-2015-0014
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Sayfa Sayısı: ss.282-289

Özet

Objective: Synthetic peptides are not sufficiently large or complex by themselves to induce immune system because of their small size. Synthetic peptides are usually conjugated to different carriers such as proteins and polyelectrolytes to enhance their immunogenic properties and antigen-specific antibody production (Abs) rate. Thus, the aim of this study is synthesis of peptide-protein covalent conjugates, and size and zeta potential analysis of these conjugates.