Tuning the gel size and LCST of N-isopropylacrylamide nanogels by anionic fluoroprobe

KOÇ K., Alveroglu E.

COLLOID AND POLYMER SCIENCE, cilt.294, sa.2, ss.285-290, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 294 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s00396-015-3779-1
  • Dergi Adı: COLLOID AND POLYMER SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.285-290
  • Anahtar Kelimeler: Nanogel, Pyranine, Poly(N-isopropylacrylamide), LCST, PRECIPITATION POLYMERIZATION, MICROSPHERES, POLY(N-ISOPROPYLACRYLAMIDE), TRANSITION, MICROGELS, HYDROGELS, BEHAVIOR
  • Yıldız Teknik Üniversitesi Adresli: Evet

Özet

Varying size fluorescent N-isopropylacrylamide (NIPAM) nanogels were synthesized from 140 to 550 nm by precipitation copolymerization. N,N-methylenebisacrylamide (BIS) and ammonium persulfate APS were used as cross-linker and initiator, respectively. 8-Hydroxypyrene-1,3,6-trisulfonic Acid (Pyranine, Py) molecules were used for controlling the particle size and lower critical solution temperature (LCST) of nanogels. NIPAM, BIS and APS amount were kept constant and Py amount changed to tailor the particle size. Fluorescence spectroscopy, atomic force microscopy and light scattering methods show that Py caused smaller size nanogels due to the electrically charged side groups. Additionally, as seen from the light scattering experiment, LCST of nanogels is getting decrease considerably with increasing Py amount. Using of Py for tuning, the gel size and LCST were found very useful, easy and effective way, and it can be used for many biomedical applications.