4.th Organic Chemistry Congress with International Participation , Antalya, Turkey, 4 - 07 October 2018, pp.89
Xanthenes and benzoxanthenes are an important class of biologically active compounds in the field of drugs and pharmaceuticals, which possess antiviral, anti-inflammatory, anticancer, and antibacterial activities1. In addition, these heterocyclic molecules have been widely used as dyes, pH-sensitive fluorescent materials for the visualization of biomolecules2.
One-pot multi-component reaction strategies offer significant advantages over two-component and stepwise reactions in several aspects by virtue of their convergence, productivity, high atom economy, facile execution1.
Metal triflates, M(OTf)x are stable in aqueous media and can act as Lewis acid catalysts in several carbon-carbon bond forming reactions3.
3,4-dihydro-12-aryl-2H-benzo[b]xanthene-1,6,11(12H)-trione compounds have been obtained through one-pot condensation of various substituted aromatic aldehydes, 2-hydroxy-1,4-naphthoquinone, and dimedone in the presence of Bi(OTf)3 as a green and reusable catalyst.