Investigation of sonophotochemical effectiveness of Schiff-base decorated novel silicon (IV) phthalocyanines with heteroaromatic moiety

KARANLIK G., CAN KARANLIK C., ERDOĞMUŞ A.

Journal of Molecular Structure, vol.1346, 2025 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 1346
  • Publication Date: 2025
  • Doi Number: 10.1016/j.molstruc.2025.143223
  • Journal Name: Journal of Molecular Structure
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chemical Abstracts Core, Chimica, Compendex, INSPEC
  • Keywords: Furan and thiophene moiety, Schiff-base, Singlet oxygen, Sonophotochemical method
  • Yıldız Technical University Affiliated: Yes

Abstract

In this study, two novel diaxially Schiff base substituted silicon (IV) phthalocyanine complexes (O-Pc and S-Pc) including heavy bromine atom have been synthesized and illuminated their molecular structures by conventional spectroscopic methods. In order to assess their potential use as sensitizers in Photodynamic Therapy (PDT) and Sonophotodynamic Therapy (SPDT) applications, photophysical, photochemical and also sonophotochemical properties have been carried out. The important parameter, singlet oxygen quantum yield (ΦΔ), was calculated as 0.35 and 0.72 for O-Pc and S-Pc, respectively, using only the light irradiation in photochemical method (PDT), while these values were increased to 1.05 using both light and ultrasound irradiation together in sonophotochemical method (SPDT). This study will contribute to the literature by revealing the ability of phthalocyanine derivative sensitizers to enhance singlet oxygen generation using the SPDT method.