Sulfur-nitrogen heterocycles from the condensation of pyrazolones and 2-iminothiazolidin-4-ones with phenyl isothiocyanate

Bagdatli E., Akkus S., YOLAÇAN Ç., Oecal N.

JOURNAL OF CHEMICAL RESEARCH, no.5, pp.302-304, 2007 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2007
  • Journal Name: JOURNAL OF CHEMICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.302-304
  • Yıldız Technical University Affiliated: Yes

Abstract

The condensation of 2-pyrazolin-5-ones with phenyl isothiocyanate, followed by reaction of the resulting thiolate ions with chloroacetyl chloride, phenacyl bromide, oxalyl chloride, 1,4-dibromo-2,3-butanedione and ethyl chloroformate, resulted in cyclisation to S,N-heterocycles in all cases. 2-Iminothiazolidin-4-ones, with phenyl isothiocyanate and then chloroacetyl chloride or phenacyl bromide, similarly formed 2,4 '-bi(thiazolidine)-derived products.