Akademik Veri Yönetim Sistemi
CUMHURIYET 8th INTERNATIONAL CONFERENCE ON APPLIED SCIENCES , Ankara, Türkiye, 23 Nisan 2023, ss.14
According to The World Health Organization (WHO), infertility is a disease of the reproductive system defined by the failure to achieve a clinical pregnancy. And it is a common disease that can be acquired for many reasons, including genetics. When it comes to human female infertility it is really hard to diagnose, particularly if it is caused by genetics. Looking at past studies, it can be seen that certain genes such as the WNT4 gene are directly linked to infertility. The present study aimed that find some other genes that may be played the role same as known genes by using bioinformatic tools. Suitable data of circRNA, miRNA, and mRNA have been collected from several datasets. After data collection, we performed a comparison analysis between the collected data and our main comparison gene the WNT4 gene by using bioinformatics tools such as Clustal Omega. Our findings indicate that the WNT4 gene and the PAX2 gene, the WNT7A gene, the WNT9B gene, and the ZP3 gene, which are also some of the genes that are directly associated with infertility, share similarities. This study is expected to contribute to future studies on this topic.