Box-Behnken Design-Desirability Function Approach in Optimization of HPLC Method for Simultaneous Determination of Ibuprofen Along with Additives in Syrup Formulation


Dinc-Zor S., Donmez O. A.

JOURNAL OF AOAC INTERNATIONAL, vol.104, no.1, pp.78-83, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 104 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.1093/jaoacint/qsaa096
  • Journal Name: JOURNAL OF AOAC INTERNATIONAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Applied Science & Technology Source, BIOSIS, CAB Abstracts, Chemical Abstracts Core, Chimica, Compendex, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database, DIALNET
  • Page Numbers: pp.78-83
  • Yıldız Technical University Affiliated: Yes

Abstract

Background: The advantages of simultaneous analyses are a decrease in analysis time and a more economical use of solvents and reagents. It is desirable that HPLC analyses possess both short term and good resolution.