Box-Behnken Design-Desirability Function Approach in Optimization of HPLC Method for Simultaneous Determination of Ibuprofen Along with Additives in Syrup Formulation


Dinc-Zor S. , Donmez O. A.

JOURNAL OF AOAC INTERNATIONAL, vol.104, no.1, pp.78-83, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 104 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.1093/jaoacint/qsaa096
  • Title of Journal : JOURNAL OF AOAC INTERNATIONAL
  • Page Numbers: pp.78-83

Abstract

Background: The advantages of simultaneous analyses are a decrease in analysis time and a more economical use of solvents and reagents. It is desirable that HPLC analyses possess both short term and good resolution.