PRODUCING AFLIBERCEPT LOADED POLY (LACTIC-co-GLYCOLIC ACID) [PLGA] NANOPARTICLES AS A NEW OCULAR DRUG DELIVERY SYSTEM AND ITS CHALLENGES


Karagoz I. K. , Allahverdiyev A. , Demircioglu A., ABAMOR E. Ş. , Dinparvar S., Bagirova M.

FRESENIUS ENVIRONMENTAL BULLETIN, cilt.30, sa.2, ss.1481-1493, 2021 (SCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Konu: 2
  • Basım Tarihi: 2021
  • Dergi Adı: FRESENIUS ENVIRONMENTAL BULLETIN
  • Sayfa Sayıları: ss.1481-1493

Özet

The aim of the present study is to develop a new drug delivery system with the aid of nanomedicine for aflibercept molecule and to evaluate optimization, characterization, in vitro drug release profile and toxicity on human retinal pigment epithelial (ARPE-19) and human retinal endothelial cell (HREC) lines.