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Karagoz I. K., Allahverdiyev A., Demircioglu A., ABAMOR E. Ş., Dinparvar S., Bagirova M.
FRESENIUS ENVIRONMENTAL BULLETIN, vol.30, no.2, pp.1481-1493, 2021 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
30
Issue:
2
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Publication Date:
2021
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Journal Name:
FRESENIUS ENVIRONMENTAL BULLETIN
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Aerospace Database, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), CAB Abstracts, Chemical Abstracts Core, Communication Abstracts, Environment Index, Geobase, Greenfile, Metadex, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
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Page Numbers:
pp.1481-1493
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Keywords:
Anti -VEGF, Drug Delivery, Nanoparticle, Retina, INTRAVITREAL BEVACIZUMAB AVASTIN, VEGF-TRAP, MACULAR DEGENERATION, INTRAOCULAR PHARMACOKINETICS, RANIBIZUMAB, INJECTION, TOXICITY, SINGLE, EYE, NEOVASCULARIZATION
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Yıldız Technical University Affiliated:
Yes
Abstract
The aim of the present study is to develop a new drug delivery system with the aid of nanomedicine for aflibercept molecule and to evaluate optimization, characterization, in vitro drug release profile and toxicity on human retinal pigment epithelial (ARPE-19) and human retinal endothelial cell (HREC) lines.