Today, negativity in both the public and private sectors can have detrimental effects on both the individual and the company he is a part of. Absenteeism at work and feelings of burnout, which are among these negative outcomes, have been increasingly prevalent in the workplace in recent years. Inability to be present at work, which is described as the inability to completely participate in work despite being at work, impacts the individual's emotions and condition in the short term, but also has long-term negative effects on the organization's working life. The idea of burnout, which develops as a result of not working, is detrimental to both the individual and the business. The mediating roles of occupational depersonalization and work safety perception in the influence of employee self-assessment on emotional tiredness according to demographics were identified, and a study model was established with hypotheses developed in this direction. Based on this context, the aim of the research was to shed light on the relationship between occupational depersonalization and the mediating roles of security perception in the effect of employee self-assessment on emotional exhaustion according to demographics. The population of the research consists of people living in Istanbul and working life. industry, the sample of the research consists of 820 participants according to the convenience sampling method. as the data collection tool of the research; Socio Demographic Questionnaire, Emotional Exhaustion Scale (EE), Depersonalization Level Scale (DP), Personal Accomplishment Perception Scale (PA) and Work Safety Importance Scale (WSP) were used. The results reveal the relationship between organizational factors affecting absenteeism and burnout. In this direction, it is estimated that the study will be beneficial for future researchers and practitioners.