Akademik Veri Yönetim Sistemi
International Food Innovation and Sustainability Congress, İstanbul, Türkiye, 16 - 18 Mayıs 2024, ss.175
Water kefir is a fermented beverage that hosts a rich microbial community and is associated with numerous health benefits. Lactic acid bacteria (LAB), crucial in the fermentation process of this beverage, can produce various extracellular polysaccharides (EPS). As naturally derived microbial polymers, EPS offer a broad spectrum of potential health benefits ranging from immune modulation to supporting gut health. Specifically, types of EPS such as dextran, produced by LAB, are utilized as stabilizers and viscosity enhancers in the pharmaceutical and food industries. However, the cellular-level effects of these components, especially regarding cytotoxicity, have not been fully understood. Our research focuses on identifying LAB strains isolated from water kefir, determining their capacities to produce EPS and dextran, and examining their cytotoxic effects. In this respect, two dextrans with various concentrations were subjected to a cytotoxic activity test using the human colon adenocarcinoma cell line, HCT116. Our findings revealed the potential of dextrans as cytotoxic agents as GRAS components.