Effect of ripening time on peptide dynamics and bioactive peptide composition in Tulum cheese

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Öztürk H. İ., Akın N.

Journal of Dairy Science, cilt.104, sa.4, ss.3832-3852, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 104 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.3168/jds.2020-19494
  • Dergi Adı: Journal of Dairy Science
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Periodicals Index Online, Agricultural & Environmental Science Database, Analytical Abstracts, BIOSIS, Business Source Elite, Business Source Premier, CAB Abstracts, Chemical Abstracts Core, EMBASE, Environment Index, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database, DIALNET
  • Sayfa Sayıları: ss.3832-3852
  • Anahtar Kelimeler: bioactive peptide, liquid chromatography–tandem mass spectrometry, peptide identification, proteolysis, Tulum cheese
  • Yıldız Teknik Üniversitesi Adresli: Hayır

Özet

Skin bag Tulum cheeses traditionally produced in the Central Taurus region of Turkey were studied to identify peptide profiles by liquid chromatography–tandem mass spectrometry over 180 d of ripening. After mass spectrometry analysis, 203 peptides were identified: 59 from αS1-casein (CN), 11 from αS2-CN, 129 from β-CN, and 4 from κ-CN. Numbers of αS1- and β-CN-derived peptides increased with increasing number of ripening days due to the dependence of newly formed peptides on proteolysis. However, similar increases were not observed for αS2- and κ-CN-derived peptides. Most identified peptides consisted of β-CN-derived peptides, followed by αS1-, αS2-, and κ-CN-derived peptides. Among these, bioactive peptides were found, including antihypertensive, antibacterial, antioxidant, dipeptidyl peptidase-4 inhibitory, metal chelating, skin regenerating, glucagon-like peptide-1 secretion enhancing, opioid, cathepsin B inhibitory, prolyl endopeptidase inhibitory, immunomodulatory, brain function improving, antiamnesic, antihypercholesterolemic, anti-inflammatory, and anticarcinogenic peptides.